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Learning bioinformatics, in bits and kmers.

A working notebook on genomics, sequencing, and the tools and algorithms behind them, written as I learn.

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  • Oct 21, 2026

    Treemmer: Downsampling massive trees while preserving tree topology

    How Treemmer (Menardo et al., 2018) shrinks a redundant phylogenetic tree one leaf at a time while keeping most of its genetic diversity, with an animation, the paper's results and a run on mpox genomes.

  • May 26, 2026

    Starting a journal on bioinformatics

    Why I'm keeping a public notebook while learning genomics and the tooling around it.

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